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Case of the week 13 ( November 2011 )
Endocrine Myopathy

 
This 58 years old man complaint is sever reading discomfort only 3 months ago , he showed me 8 prespyopic prescriptions described within 2 months by 8 different ophthalmologists  , still he can't read neither binoculary nor monoculary , he stopped his well known private business , one of my colleagues advised him to be examined by a strabismologists

Examination showed that with this disorder, reading becomes almost impossible



See video examination of this patient

 

         

I've encountered many patients with well manifest thyroid eye disease ( TED ) who were not aware of their illness - like this man - where the scleral show and his left exophthalmic eye could be noticed easily faraway .

I've also observed many TED patients in whom exophthalmos developed after the onset of the motility defect . Others did not develop exophthalmos at all and represented only by motility disorders.

 In TED, limitation of elevation is the most common ocular motility disorder ;this, followed by limitation of horizontal gaze . Bilateral myopathy of the medial recti may lead to the characteristic convergence insufficiency which is a prominent feature in this patient, leading to sever discomfort at near work .

Work up of this patient :

1. Thyroid function tests .

2. Ophthalmoscopy , OCT optic nerve , Perimetery (Compression of the orbital apex by the enlarged extraocular muscles, especially the medial rectus , may cause congestion of the optic nerve and decrease in visual acuity ) .

3. MRI orbit ( looking for the characteristic MR muscle enlargement with sparing of the tendon - Coca cola bottle appearence ) .

Management suggested :

Of course , first to be managed is the hormonal disorder , if optic nerve congestion is suspected steroid therapy could be applied .   

Therapy for convergence insufficiency is the work of orthoptics. Indeed its treatment is the most successful application of orthoptics and in most cases provides long-lasting symptomatic relief .  The ophthalmologist must remember that in TED convergence insufficiency is a reversible disorder and that the decision to perform surgery should be made with extreme cautious and not until all other therapeutic possibilities, including prisms base-in, have been tried. If surgery is imperative, I advocate BMR resection .

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